医学
血栓形成
血栓
纳米医学
静脉血栓形成
脂质体
重症监护医学
外科
纳米技术
纳米颗粒
材料科学
作者
Vishnu Priya,Matte Kasi Viswanadh,Abhishesh Kumar Mehata,Dharmendra Jain,Sanjeev K. Singh,Madaswamy S. Muthu
出处
期刊:Nanomedicine
日期:2021-06-01
卷期号:16 (13): 1153-1176
被引量:8
标识
DOI:10.2217/nnm-2021-0058
摘要
Currently available anti-thrombotic therapy for the prophylaxis and treatment of arterial and venous thrombosis includes intravenous administration of anti-thrombotic drugs which lead to severe bleeding risks such as cerebral hemorrhage and stroke. Targeting approaches that utilize nanosystems to reach the thrombus sites are emerging to increase the local effect of anti-thrombotic drugs, as well as to decrease these severe bleeding complications by diminishing the systemic availability of these drugs. This review emphasizes the emerging targeted nanomedicines (liposomes, micelles, polymeric nanoparticles, material bases nanoparticles and other biological vectors) for the prophylaxis and treatment of thrombotic events as well as multifunctional nanomedicines for theranostic applications. Nanomedicine offers a promising platform for a smart, safe, and effective approach for the management of thrombosis.
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