疾病
医学
淋巴白血病
骨髓移植
移植
重症监护医学
干细胞
肿瘤科
白血病
内科学
生物
遗传学
作者
Nicola Gökbuget,Roberto Bassan,Hervé Dombret,Michael Doubek,Adele K. Fielding,R. Foà,Sebastian Giebel,D. Hoelzer,G. Martinelli,G Meloni,A Moicean,O. Ottmann,Pier Paolo Piccaluga,J. M. Ribera,P Rousselot,Jan Walewski
出处
期刊:Uni-Med Verlag AG eBooks
[Uni-Med Verlag AG]
日期:2011-01-01
被引量:1
摘要
Acute lymphoblastic leukemia (ALL) is a malignant disease of lymphatic cells in the bone marrow or other organs of the lymphoid system with a number of unique features. Cure rates were improved in the past decades first in children and later in adults from less than 10% to 40-50% and even >50% in distinct subgroups. Important progress was also achieved in basic research, particularly in molecular genetics. The progress in terms of diagnosis and treatment of ALL has stemmed mainly from systematic clinical research by a number of cooperative study groups. It is based on optimisation of chemotherapy, stem cell transplantation, supportive care integrated in risk adapted treatment strategies and more recently complemented by approaches for targeted therapy. The book gives an overview on the current strategies for management of adult ALL including approaches to rare entities and specific situations. It represents the result of a structured consensus process conducted by the members of the European Working Group for Adult ALL.
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