超分子化学
纳米技术
材料科学
两亲性
药物输送
聚合物
自组装
高分子
小泡
超分子聚合物
生物污染
胶束
高分子科学
膜
化学
共聚物
有机化学
分子
水溶液
复合材料
生物化学
作者
Yongfeng Zhou,Wei Huang,Jinyao Liu,Xinyuan Zhu,Deyue Yan
标识
DOI:10.1002/adma.201000369
摘要
Abstract Hyperbranched polymers (HBPs) are highly branched macromolecules with a three‐dimensional dendritic architecture. Due to their unique topological structure and interesting physical/chemical properties, HBPs have attracted wide attention from both academia and industry. In this paper, the recent developments in HBP self‐assembly and their biomedical applications have been comprehensively reviewed. Many delicate supramolecular structures from zero‐dimension (0D) to three‐dimension (3D), such as micelles, fibers, tubes, vesicles, membranes, large compound vesicles and physical gels, have been prepared through the solution or interfacial self‐assembly of amphiphilic HBPs. In addition, these supramolecular structures have shown promising applications in the biomedical areas including drug delivery, protein purification/detection/delivery, gene transfection, antibacterial/antifouling materials and cytomimetic chemistry. Such developments promote the interdiscipline researches among surpramolecular chemistry, biomedical chemistry, nanotechnology and functional materials.
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