Perfluorocarbon-based O2 nanocarrier for efficient photodynamic therapy

A series of polymer micelles with a perfluorocarbon (PFC) core to carry both PS and O₂ to tumor sites was prepared. These new PFC formulation not only improved the production of ¹O₂ and enhanced the PDT efficiency, but also significantly reduced cell toxicity compared with the one without a perfluoro unit.