Determination of bisphenol A in barreled drinking water by a SPE–LC–MS method

A quantitative method was established to determine the well-known endocrine disruptor bisphenol A (BPA) in barreled drinking water. Samples were pretreated by solid phase extraction (SPE), and then analyzed by liquid chromatography-mass spectrometry (LC-MS). Working standard solutions were obtained by pretreatment of a series of aqueous standard solutions over the concentration range of 122.9-1190.7 ng L^-1. The linear calibration curve was Y = 69.4X + 2206.2 with the correlation coefficient (R²) of 0.9929. The average recoveries from spiked samples were more than 91.6%. The relative standard deviations (n = 6) were less than 9.6%. The method allowed the detection of 7.0 ng L^-1 BPA in barreled drinking water. Typical barreled drinking water products in the market were detected. As results, thirty-five of fifty-two commercial samples were found to contain BPA with a maximum concentration of 898.7 ng L^-1. The occurrence of BPA in barreled drinking water may be due to the pollution of raw water, the inefficiency of purification processes and the migration of BPA from barrels. The daily exposure of adults to BPA through drinking barreled drinking water is far below the current human tolerable daily intake (TDI) set by European Food Safety Authority (EFSA).