医学
吡格列酮
危险系数
内科学
胰岛素抵抗
糖尿病
安慰剂
心肌梗塞
冲程(发动机)
心脏病学
置信区间
2型糖尿病
胰岛素
内分泌学
病理
替代医学
工程类
机械工程
作者
Walter N. Kernan,Catherine M. Viscoli,Karen L. Furie,Lawrence H. Young,Silvio E. Inzucchi,Mark Gorman,Peter Guarino,Anne M. Lovejoy,Peter Peduzzi,Robin Conwit,Lawrence Brass,Gregory G. Schwartz,Harold P. Adams,Léo Berger,Antonio Carolei,Wayne M. Clark,Bruce M. Coull,Gary A. Ford,Dawn Kleindorfer,John R. O’Leary
标识
DOI:10.1056/nejmoa1506930
摘要
Patients with ischemic stroke or transient ischemic attack (TIA) are at increased risk for future cardiovascular events despite current preventive therapies. The identification of insulin resistance as a risk factor for stroke and myocardial infarction raised the possibility that pioglitazone, which improves insulin sensitivity, might benefit patients with cerebrovascular disease.
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