Juvenile xanthogranuloma with angiomatous appearance and a peculiar immunophenotype

Abstract Juvenile xanthogranuloma is the most common form of non‐Langerhans cell histiocytosis in childhood. The clinical differential diagnosis of a solitary juvenile xanthogranuloma includes molluscum contagiosum, Spitz nevus, and melanoma. Lesions larger than 2 cm in diameter may be misdiagnosed as hemangiomas, but this is not typical of smaller juvenile xanthogranuloma. We report a case of solitary juvenile xanthogranuloma in a 10‐year‐old boy with angiomatous appearance and peculiar immunophenotype.