The effect of the cross-linker ratio used in gellan gum biomaterial synthesis on biomineralization

The first step in using polymeric materials for many applications is their crosslinking. Before application, the cross-linker used in crosslinking should be kept at an optimum ratio. The use of gellan gum, a polymeric material, as an intra-body biomaterial is also included in these application areas. In this study, the effect of CaCl2 ratio used as GG cross-linker on the biomineralization of the obtained GG hydrogel was investigated. FTIR, XRD, SEM and EDS analyzes of the synthesized and lyophilized cross-linked GG samples were performed before and after biomineralization. In line with the results obtained, it was observed that the bioactivity of the GG hydrogel could be changed by changing the cross-linking ratio.