Electrosynthesis of 1,3,5-trisubstituted 1,2,4-triazoles from phenylhydrazine, aldehydes and amines under mild conditions

A simple and convenient method for the electrosynthesis of 1,3,5-trisubstituted 1,2,4-triazoles with three components of phenylhydrazine, aldehydes and amines has been established. The electrolysis could be smoothly carried out at room temperature without additional strong oxidants and catalysts to afford the target product in good yields. This electrochemical route effectively extends synthetic field of 1,2,4-triazole derivatives. To create your abstract, type over the instructions in the template box below. Fonts or abstract dimensions should not be changed or altered. • Without using additional strong oxidants and metal catalysts. • With easily available starting materials, the route has potential applications. • One-pot three-component reaction under mild conditions.