蛋白激酶B
癌症研究
PI3K/AKT/mTOR通路
黑色素瘤
肿瘤进展
信号转导
化学
医学
内科学
细胞生物学
生物
癌症
作者
Chi–Che Hsieh,Yue‐Chiu Su,Kuan-Ying Jiang,Takamichi Ito,Tingwei Li,Yumiko Kaku‐Ito,Shih‐Tsung Cheng,Li‐Tzong Chen,Daw‐Yang Hwang,Che‐Hung Shen
标识
DOI：10.1016/j.jare.2022.03.005
摘要
TRPM1 promotes tumor progression and malignancy in acral melanoma by activating the Ca2+/CaMKIIδ/AKT pathway. CaMKII inhibition may be a potential therapeutic strategy for treating acral melanomas with high expression of TRPM1.
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(2025-6-4)
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