Elimination of Zero‐Quantum Interference in Two‐Dimensional NMR Spectra

The simultaneous application of a swept-frequency pulse and a gradient pulse Gf enables z-magnetization to be distinguished from zero-quantum coherence (see picture). This new and highly effective method enables the elimination of strong interference caused by zero-quantum coherence, which is often present in NOESY, TOCSY, and many other types of NMR spectra obtained by traditional methods of signal selection, and can be readily implemented on any modern NMR spectrometer.