医学
CCL5
趋化因子
心肌梗塞
心功能曲线
心脏病学
内科学
炎症
心力衰竭
免疫学
T细胞
免疫系统
白细胞介素2受体
作者
Fabrizio Montecucco,Vincent Braunersreuther,Sébastien Lenglet,Bénédicte M. A. Delattre,Graziano Pelli,Vanessa Buatois,François Guilhot,Katia Galan,Nicolas Vuilleumier,Walter Ferlin,Nicolas Fischer,Jean‐Paul Vallée,Marie Kosco‐Vilbois,François Mach
标识
DOI:10.1093/eurheartj/ehr127
摘要
Treatment with anti-CCL5 mAb significantly reduced both infarct size and post-infarction heart failure in a mouse model of chronic cardiac ischaemia. Cardioprotective effects were associated with the reduction of leucocyte recruitment within infarcted hearts.
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