Fluorescent Characteristics of Quantum Dots in the Application of Bio-labeling Imaging

As newly developed fluorescence labels,compare to the traditional organic fluorescent dyes,the semiconductor quantum dots(QDs) are of many advantages,such as broaden and continuous excitation,narrower and more symmetric emission,photochemical stability,longer fluorescence lifetime,higher quantum yield and lower biological toxicity,and so on.These properties make quantum dots(QDs) unique and superior in the applications of cell labeling and tracking and imaging in vivo.It was widely applied in many areas of life science.It breaks through many defects,such as fluorescence performance and biological toxicity,compared to the traditional organ-ic fluorescent dyes.The application of quantum dots(QDs) has greatly promoted the research work of ultra-sensitive,in situ,real-time and dynamic bio-tracking and bio-imaging in life sciences.In this paper,the fluorescent properties of quantum dots and the application of cell labeling and tracking imaging in vivo are reviewed,and the prospects in Fluorescence in situ hybridization,flow cytometry,Re-al-time quantitative fluorescence PCR are envisioned.