Diabetes is divided into type 1 diabetes and type 2 diabetes.The incidence of diabetes is related to genetic factors,environmental factors and stress factors.The incidence of type 2 diabetes is closely related to obesity,so obesity is one of the most important risk factors that lead to type 2 diabetes.Insulin resistance is the core mechanism for obesity leading to type 2 diabetes.The purpose of this review is to investigate the correlation between obesity and diabetes and the mechanism which leads to diabetes,and to take effective measures for its control.