Study on the Cervical Infection and the Cervical Cancer

Objective To investigate the relationship between the HPV,HSV-2,HCMV,and CT cervical infection and cervical cancer.Method Samples from women with cervical carcinoma(40 subjects),cervical inflammation(60 subjects),and normal subjects(60) were analyzed.PCR,DNA genotyping,and thin prep cytological test were used in the identification of the pathogens.Result Compared with the samples from the normal subjects(11.67%),97.5% of samples from cervical cancer patients had HPV16、18、31、33、35、52、58 infection.The difference between these two group is highly significant(P 0.001).The percentage of HPV6、11,HSV-2,HCMV,and CT infection in the samples from cervical cancer patients was 47.5%,20%,10%,and 35%,respectively.The percentage of HPV6、11,HSV-2,HCMV,and CT infection in the normal samples was 20%,10.83%,7.5%,and 20.83%,respectively.The differences in the infection rates of these 4 types of pathogens between the normal and cancer patients were not significant(P 0.05).Correlation of infection by these four pathogens was also not observed.Conclusion HPV infection is the major risk factor for cervical cancer.There is no significant correlation between cervical cancer and infection with HPV6、11,HSV-2,HCMV,and CT.