The Meta-analysis of Diabetic Peripheral Neuropathy for Treating by α-lipoic Acid

Objective By using the Meta analysis,to estimate the effect of diabetic peripheral neuropathy for treating by α- lipoic acid.Methods Collected and integrated the relevant literature about diabetic peripheral neuropathy for treating by α- lipoic acid,which had published from January 2010 to December 2014,combined with the available data,analyzed the effect of diabetic peripheral neuropathy for treating by α- lipoic acid.Results Through the analysis of 5 articles,it ultimately found that compared to accept other drugs in the treatment of the patients in the control group,the therapeutic effect of diabetic peripheral neuropathy for treating byα- lipoic acid for the patients in the observation group were significantly better,and the period of hospitalization in patients with no obvious discomfort or adverse reaction.According to Meta analysis,it found that combined with RR=1.28,95%confidence interval(C1)to(1.3,1.60).Conclusion The treatment of diabetic peripheral neuropathy with α-lipoic acid is obvious,which is suitable for clinical application.