Effect of irbesartan combined with levoamlodipine in treatment of patients with hypertension and proteinuria

Objective To observe the effect of irbesartan combined with levoamledipine in patients with hypertension and proteinuria. Methods Ninety patients with hypertension and proteinuria were randomly divided into two groups. Group A of 46 patients received irbesartan 150 mg po qd and levoamlodipine 2. 5 mg po qd,Group B of 46 patients received levoamlodipine 2. 5 mg po qd and hydrochlorthiazide 12. 5 mg po qd for 6 months. Blood pressure( BP),24 h urinary albumin were measured before and after treatment. Results After 6 months,both of two groups can efficiently reduce blood pressure,proteinuria. In contrast,the proteinuria in group A was significantly reduced than that of group B after treatment. Conclusion Irbesartan combined with levoamlodipine can remarkably decrease BP and proteinuria and better protect renal function.