Application of Propofol Combined Ketamine and Lidocaine Intravenous Anesthesia in Short Pediatric Operations

Objective To compare the safety and feasibility of propofol combined with ketamine and lidocaine intravenous anesthesia with ketamine intravenous anesthesia in short pediatric operation.Methods Fifty children ASAⅠ～Ⅱ,aged 3-11,were randomly devided into two groups;the group of ketamine(K)(n=25) and the group of propofol combined with ketamine and lidocaine(C)(n=25).Anesthetic induction:Ketamine 2 mg·kg~(-1) was infused in group K and mixed liquor of propofol combined with ketamine and lidocaine(PKL) 0.2 mL·kg~(-1) in group C in one minutes.Anesthetic maintance:Ketamine was administerd by pumping at the rate of 2～4 mg/(kg·h)~(-1) in group K and PKL mixed liquor 0.2～0.4 mL/(kg·h)~(-1) in group C,and.Results There was a significant increase in MAP and HR in group K(P0.05),and there was no significant difference in group C(P0.05).There was no significant difference in SPO_2 between two group(P0.05).Conscious time was shorter in group C than group K(P0.05).Incidence of postoperative restlessness and nausea and vomiting was lower in group C tha group K(P0.05).Conclusion Compared with ketamine intravenous anesthesia,propofol combined ketamine and lidocaineintravenous anesthesia is more steady and faster to awake after operation and more suitable to short pediatric operation.