Fe-POM Anchored on mSiO 2 -Coated Upconversion Nanoparticles for Cascading Catalytic Nano-Synergistic Therapy

. This process maintains the reaction cycle. This continuous cycling occurs in the tumor microenvironment and consumes intracellular GSH. Due to this consumption, the tumor's antioxidant defense weakens. Thus, the therapeutic effect of CDT increases. This strategy, combined with the imaging capability of UCNPs, demonstrates excellent antitumor performance.