Fe3+-based nanovesicle mediated transferrin hijacking for glioblastoma stem cell tumoricidal treatment and postoperative recurrence inhibition

released from hemoglobin in RNVs to create a feedback loop that amplifies ferroptosis effects, enhancing the chemotherapeutic efficacy of temozolomide against GSCs. This Tf-hijacking nanovesicle enables GSC tumoricidal treatment and provides a novel approach for GBM postoperative recurrence inhibition.