[Consensus on standardized diagnosis and treatment of diseases at the choledocho-pancreatico-duodenal junction(2026)].

The choledocho-pancreatico-duodenal junction (CPDJ) refers to the specific anatomical region where the bile duct,pancreatic duct,and duodenum converge,which is prone to various diseases,including inflammation,stones,tumors,malformations,injuries, and functional disorders. The common clinical manifestations of diseases at the CPDJ are caused by obstruction of the bile duct,pancreatic duct,and duodenum. Unexplained biliary and/or pancreatic duct dilation refers to the clinical sign of bile duct and/or pancreatic duct dilation observed on imaging without an apparent space-occupying lesion. Such patients may be asymptomatic and have normal laboratory test results,or they may only exhibit mild elevations in alkaline phosphatase, γ-glutamyl transpeptidase,and bilirubin levels. Among these cases, some biliary and pancreatic duct dilations are physiological,while others are caused by early-stage or atypical tumors that are not easily detectable on imaging. Currently, there is a lack of unified understanding in the clinical diagnosis and treatment of diseases at the CPDJ,particularly unexplained biliary and pancreatic duct dilation, leading to frequent cases of missed diagnosis, misdiagnosis, and overtreatment. This consensus aims to standardize the diagnosis and treatment process for diseases at the CPDJ, enhance professionals' understanding of the complexity, specificity,and common characteristics of these diseases,and minimize missed diagnoses, misdiagnoses,nonstandard treatments,and overtreatment to the greatest extent possible.