副球虫病
巴西副球虫病
医学
副球虫病
流行病学
疾病
慢性肉芽肿性疾病
免疫学
重症监护医学
病理
作者
Flá vio de Queiroz-Telles,Paula M. Peçanha‐Pietrobom,Marcos Rosa Júnior,Rodrigo de Melo Baptista,Paulo Mendes Peçanha
出处
期刊:Seminars in Respiratory and Critical Care Medicine
[Georg Thieme Verlag KG]
日期:2020-01-30
卷期号:41 (01): 053-068
被引量:20
标识
DOI:10.1055/s-0039-3400544
摘要
Abstract Paracoccidioidomycosis (PCM) is one of the most relevant systemic endemic mycoses in Latin American countries, especially in South American countries, with endemic and hyperendemic areas. The real burden of PCM may be underestimated because of a lack of compulsory case notification. Recent phylogenetic data revealed that Paracoccidioides brasiliensis comprises several cryptic species including P. brasiliensis and P. lutzii. However, the genetic biodiversity of Paracoccidioides does not affect the clinical manifestations or therapeutic response to therapy. Lung involvement is a common finding, especially in patients experiencing the chronic form of the disease, and, because of its similarities with tuberculosis, clinicians must be alert to the possibility of PCM in patients with chronic respiratory manifestations and epidemiological risk factors for this fungal disease.
科研通智能强力驱动
Strongly Powered by AbleSci AI