Re-understand the clinical significance of natriuretic peptide family

Although BNP/NT-proBNP has been widely accepted as the gold standard biomarker for the diagnosis and prognosis of heart failure (recommendation level: ⅠA), the latest studies show that some of the previous knowledge of the test results of BNP/NT-proBNP are wrong. It is important for clinical and laboratory physicians to understand the latest progress on natriuretic peptide family in order to use BNP/NT-proBNP more properly.In the future, as the new drugs, which work via natriuretic peptide family, be used widely in patients, the test of natriuretic peptide family will become more important.(Chin J Lab Med, 2017, 40: 414-416) Key words: Heart failure; Natriuretic peptide, brain; Peptide fragments; Neprilysin; Angiotensin receptor antagonists