Hypervalent Iodine Compounds as Precursors for Biomedical Radiotracers

Abstract This chapter summarizes the increasing role that hypervalent aryliodine compounds, especially aryliodine(III) compounds, are serving as precursors for biomedical radiotracers due to their ease of synthesis, often adequate storage stabilities, and high reactivities in useful labeling reactions, especially those with short‐lived [ 18 F]fluoride ion ( t 1/2 = 109.8 min) for producing radiotracers for imaging with positron emission tomography.