肌萎缩侧索硬化
C9orf72
药效学
医学
神经科学
病理
药理学
生物
疾病
药代动力学
失智症
痴呆
作者
Tania F. Gendron,Jeannie Chew,Jeannette N. Stankowski,Lindsey R. Hayes,Yong‐Jie Zhang,Mercedes Prudencio,Yari Carlomagno,Lillian M. Daughrity,Karen Jansen‐West,Emilie A. Perkerson,Aliesha D. O’Raw,Casey Cook,Luc Pregent,Véronique Belzil,Marka van Blitterswijk,Lilia J. Tabassian,Chris W. Lee,Mei Yue,Jimei Tong,Yuping Song
标识
DOI:10.1126/scitranslmed.aai7866
摘要
Poly(GP) proteins are a promising pharmacodynamic marker for developing and testing therapeutics for treating C9ORF72 -associated amyotrophic lateral sclerosis.
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