Cavitary lung cancer with cartilage tissues in the wall mimicking aspergilloma

A 65-year-old female presented with a cavitary lesion in the right upper lung field (figure 1A). The diagnosis was aspergilloma because of the chest CT appearance of a fungus ball-like mass in the cavity (figure 1B) and treatment was started with itraconazole (200 mg/day). However, the cavitary lesion enlarged over a period of 6 months (figure 1C), with a C-reactive protein (CRP) level under 0.5 mg/dL. The patient was referred to our hospital and microscopic examination of a transbronchial lung biopsy of the cavitary lesion revealed lung cancer. A right upper lobectomy was performed. Histologically, pleomorphic carcinoma, confirmed …