STRUCTURAL ANALYSIS OF THE HUMAN α‐FETOPROTEIN GENEa

Annals of the New York Academy of SciencesVolume 417, Issue 1 p. 13-20 STRUCTURAL ANALYSIS OF THE HUMAN α-FETOPROTEIN GENEa Taiki Tamaoki, Taiki Tamaoki Department of Medical Biochemistry, Faculty of Medicine, University of Calgary, Calgary, Alberta T2N 4N1, CanadaSearch for more papers by this authorTomonori Morinaga, Tomonori Morinaga Department of Medical Biochemistry, Faculty of Medicine, University of Calgary, Calgary, Alberta T2N 4N1, CanadaSearch for more papers by this authorMasaharu Sakai, Masaharu Sakai Department of Medical Biochemistry, Faculty of Medicine, University of Calgary, Calgary, Alberta T2N 4N1, CanadaSearch for more papers by this authorGeoffrey Protheroe, Geoffrey Protheroe Department of Medical Biochemistry, Faculty of Medicine, University of Calgary, Calgary, Alberta T2N 4N1, CanadaSearch for more papers by this authorYoshio Urano, Yoshio Urano Department of Medical Biochemistry, Faculty of Medicine, University of Calgary, Calgary, Alberta T2N 4N1, CanadaSearch for more papers by this authorThomas G. Wegmann, Thomas G. Wegmann Department of Immunology, Faculty of Medicine, University of Alberta, Edmonton, Alberta T6G 2H7, CanadaSearch for more papers by this author Taiki Tamaoki, Taiki Tamaoki Department of Medical Biochemistry, Faculty of Medicine, University of Calgary, Calgary, Alberta T2N 4N1, CanadaSearch for more papers by this authorTomonori Morinaga, Tomonori Morinaga Department of Medical Biochemistry, Faculty of Medicine, University of Calgary, Calgary, Alberta T2N 4N1, CanadaSearch for more papers by this authorMasaharu Sakai, Masaharu Sakai Department of Medical Biochemistry, Faculty of Medicine, University of Calgary, Calgary, Alberta T2N 4N1, CanadaSearch for more papers by this authorGeoffrey Protheroe, Geoffrey Protheroe Department of Medical Biochemistry, Faculty of Medicine, University of Calgary, Calgary, Alberta T2N 4N1, CanadaSearch for more papers by this authorYoshio Urano, Yoshio Urano Department of Medical Biochemistry, Faculty of Medicine, University of Calgary, Calgary, Alberta T2N 4N1, CanadaSearch for more papers by this authorThomas G. Wegmann, Thomas G. Wegmann Department of Immunology, Faculty of Medicine, University of Alberta, Edmonton, Alberta T6G 2H7, CanadaSearch for more papers by this author First published: December 1983 https://doi.org/10.1111/j.1749-6632.1983.tb32843.xCitations: 3 a This work was supported by the National Cancer Institute of Canada, the Medical Research Council of Canada, and the Alberta Heritage Savings Trust Fund. AboutPDF ToolsRequest permissionExport citationAdd to favoritesTrack citation ShareShare Give accessShare full text accessShare full-text accessPlease review our Terms and Conditions of Use and check box below to share full-text version of article.I have read and accept the Wiley Online Library Terms and Conditions of UseShareable LinkUse the link below to share a full-text version of this article with your friends and colleagues. Learn more.Copy URL Share a linkShare onEmailFacebookTwitterLinkedInRedditWechat References 1 Law, S. W., T. Tamaoki, F. Kreuzaler & A. Dugaiczyk 1980. Molecular cloning of DNA complementary to a mouse α-fetoprotein mRNA sequence. Gene 10: 53–61. 2 Law, S. W. & A. Dugaiczyk 1981. Homology between the primary structure of α fetoprotein, deduced from a complete cDNA sequence, and serum albumin. Nature 291: 201–205. 3 Gorin, M. B., D. L. Cooper, F. Eiferman, P. van de Rijn & S. M. Tilghman 1981. The evolution of α-fetoprotein and albumin 1. A comparison of the primary amino acid sequences of mammalian α-fetoprotein and albumin. J. Biol. Chem. 256: 1954–1959. 4 Kioussis, D., F. Eiferman, P. van de Rijn, M. B. Gorin, R. S. Ingram & S. M. Tilghman 1981. The evolution of α-fetoprotein and albumin 11. The structures of the α-fetoprotein and albumin genes in the mouse. J. Biol. Chem. 256: 1960–1967. 5 Innis, M. A., M. M. Harpold & D. L. Miller 1979. Amplification of α-fetoprotein complementary DNA by insertion into bacterial plasmid. Arch. Biochem. Biophys. 195: 128–135. 6 Liao, W. S. L., R. W. Hamilton & J. M. Taylor 1980. 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Alpha-fetoprotein. Structure and expression in man and inbred mouse strains under normal conditions and liver injury. Johns Hopkins Med. J. Suppl. 3: 249–255. 19 Yachnin, S., R. Hsu, R. L. Heinrikson & J. B. Miller 1977. Studies on human α fetoprotein. Isolation and characterization of monomeric and polymeric forms and aminoterminal sequence analysis. Biochim. Biophys. Acta 493: 418–428. 20 Aoyagi, Y., T. Ikenaka & F. Ichida 1977. Comparative chemical structures of human α-fetoproteins from fetal serum and from ascites fluid of a patient with hepatoma. Cancer Res. 37: 3663–3667. 21 Breathnach, R., C. Benoist, K. O'Hara F. Gagnon & P. Chambon 1978. Ovalbumin gene: Evidence for a leader sequence in mRNA and DNA sequences at the exon-intron boundaries. Proc. Natl. Acad. Sci. USA 75: 4853–4857. 22 Eiferman, F. A., P. R. Young, R. W. Scott & S. M. Tilghman 1981. Intragenic amplification and divergence in the mouse α-fetoprotein gene. Nature 294: 713–718. 23 Young, P., R. W. Scott, D. H. Hamer & S. M. Tilghman 1982. Construction and expression in vivo of an internally deleted mouse α-fetoprotein gene: Presence of a transcribed Alu-like repeat within the first intervening sequence. Nucleic Acids Res. 10: 3099–3116. 24 Lawn, R. M., J. Adelman, S. C. Bock, A. E. Franke, C. M. Houck, R. C. Najatrian, P. H. Seeberg & K. Wion 1981. The sequence of human serum albumin cDNA and its expression in E. coli. Nucleic Acids Res. 9: 6103–6114. 25 Dugaiczyk, A., S. W. Law & O. E. Dennison 1982. Nucleotide sequence and the encoded amino acids of human serum albumin mRNA. Proc. Natl. Acad. Sci. USA 79: 71–75. 26 Morinaga, T., M. Sakai, T. G. Wegmann & T. Tamaoki 1983. The primary structures of human α-fetoprotein and its messenger RNA. Proc. Natl. Acad. Sci. USA. In press. Citing Literature Volume417, Issue1Oncodevelopmental Biology and MedicineDecember 1983Pages 13-20 ReferencesRelatedInformation