凝聚态物理
磁化
偶极子
电场
磁场
磁偶极子
极化密度
极化(电化学)
铁电性
材料科学
磁性纳米粒子
哈密顿量(控制论)
本地字段
纳米颗粒
物理
纳米技术
化学
电介质
量子力学
数学优化
光电子学
数学
物理化学
作者
A. Apostolov,I. N. Apostolova,Steffen Trimper,J. M. Wesselinowa
标识
DOI:10.1002/pssb.202200523
摘要
Magnetoelectroporation is an effective method of opening nanopores in cell membranes using magnetoelectric nanoparticles (MENPs) for the purpose of in vivo and in vitro delivery of drug substances to cancer cells. A microscopic approach is proposed as theoretical basis for that phenomenon. The underlying Hamiltonian includes the magnetic and ferroelectric subsystems characterized by two‐order parameters. The related magnetoelectric coefficient α HE characterizes the relationship between the applied magnetic field and a generated local electric field. Whereas the spontaneous polarization of the MENP is due to the arrangement of electric dipoles, there appears an additional spin‐assisted polarization owing to the magnetic phase transition. It is shown that the main contribution to the local field comes from . Moreover, the local electric field depends on the orientation of the easy‐axis magnetization of the MENPs with respect to applied external magnetic field. The magnetoelectric coefficient exhibits a nonlinear dependence on the external magnetic field. The results are based on an analytical Green's function method. The numerical calculations are performed for spherical, structurally heterogeneous nanoparticles composed on a core and a shell, where the noninteracting nanoparticles have the same diameter of 25 nm. The results are in qualitative agreement with experimental observations.
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