吲唑
化学
胺化
区域选择性
催化作用
铜
药物化学
组合化学
有机化学
作者
Lina Zhang,Hao Yan,Yueyue Fan,Xiande Luo,Yingqiao Pan,Yishu Liu,Yuepiao Cai,Xiaodong Bao
标识
DOI:10.1021/acs.joc.3c00187
摘要
A copper-catalyzed C3 amination of 2H-indazoles with 2H-indazoles and indazol-3(2H)-ones under mild conditions was developed. A series of indazole-containing indazol-3(2H)-one derivatives were produced in moderate to excellent yields. The mechanistic studies suggest that the reactions probably proceed through a radical pathway.
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