医学
痴呆
维生素D与神经学
优势比
碱性磷酸酶
维生素D缺乏
内科学
横断面研究
逻辑回归
生理学
胃肠病学
老年学
内分泌学
生物
病理
疾病
生物化学
酶
作者
Narjara Pereira Leite,Tatiana Souza Alvarez,Fernando Luiz Affonso Fonseca,Sônia Hix,Roseli Oselka Saccardo Sarni
出处
期刊:Revista Da Associacao Medica Brasileira
[SciELO]
日期:2023-01-01
卷期号:69 (1): 61-65
被引量:5
标识
DOI:10.1590/1806-9282.20220613
摘要
OBJECTIVE: The aim of this study was to evaluate serum 25(OH)D concentrations in the homebound elderly people and relate them to level of dementia, nutritional risk, and route of dietary administration. METHODS: This is a cross-sectional study involving 207 bedridden elderly people assisted by the Home Care Service in the city of Santo André – SP, from June to December 2016. The following factors were evaluated: dietary intake of vitamin D, arm circumference, triceps skin fold thickness, calf circumference, nutritional risk by Mini-Nutritional Assessment, level of dementia by the adapted Clinical Dementia Rating questionnaire, and laboratory tests such as serum concentrations of 25(OH)D, ultrasensitive C-reactive protein, alkaline phosphatase, serum calcium, and parathormone. RESULTS: The mean age of the elderly people was 81.6 (9.2) years. Deficiency of 25(OH)D was observed in 76.3% of the elderly people. There was an inverse correlation between serum concentrations of 25(OH)D: parathormone (r=-0.418, p<0.001) and alkaline phosphatase (r=-0.188, p=0.006) and a direct correlation with serum calcium (r=-0.158, p=0.022). Logistic regression showed that vitamin D deficiency was directly and independently associated with oral feeding (odds ratio 7.71; 95%CI 2.91–20.40). CONCLUSION: Bedridden households showed high prevalence of vitamin D deficiency without association with nutritional risk and level of dementia. Oral diet was associated with vitamin D deficiency, possibly due to low consumption of source foods.
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