Versatile Room‐Temperature Phosphorescence Silk Fibroin Platforms for Sustainable and Biocompatible Multifunctional Interfaces

Abstract The development of sustainably sourced, biocompatible room‐temperature phosphorescence (RTP) materials with rich formats, multimodal tunability, and multifunctional capabilities presents a transformative opportunity for sustainable technologies and biomedical interfaces, yet it remains a significant challenge. Here, RTP silk fibroin systems that feature improved processability, responsiveness, and functionality by multivalently anchoring phosphors to a versatile protein matrix are reported. The RTP silk fibroin can be processed into various fully biodegradable platforms, exhibiting strong RTP emission with a lifetime of up to 233 ms driven by multiple robust phosphor–fibroin interactions. The resulting platforms exhibit multi‐responsiveness to UV light, vapor, and temperature, along with diversified functionalities that include recyclability, weldability, morphability, and adhesion. Moreover, their adaptability with diverse micro/nano‐processing techniques enables complex RTP patterning and multidimensional information integration. Finally, it is demonstrated that these convergent advantages endow the platforms with multifunctionality and multi‐interface compatibility, enabling applications such as smart labels for electronic devices, conformal networks for pharmaceuticals, and scalable textiles for face masks.