Detection of residual stones by peroral direct cholangioscopy in patients with intrahepatic stones after hepaticojejunostomy: a prospective study (with video)

医学 前瞻性队列研究 普通外科 胃肠病学 内科学
作者
Kazuyuki Matsumoto,Hironari Kato,Akihiro Matsumi,Kazuya Miyamoto,Kosaku Morimoto,Yuki Fujii,Ryosuke Sato,Nao Hattori,Taisuke Obata,Hiroyuki Terasawa,Daisuke Uchida,Shigeru Horiguchi,Koichiro Tsutsumi,Motoyuki Otsuka
出处
期刊:Gastrointestinal Endoscopy [Elsevier BV]
卷期号:100 (3): 457-463 被引量:1
标识
DOI:10.1016/j.gie.2024.04.014
摘要

Background and Aims The difficulty of radiographic confirmation of the presence of stones remains a challenge in the treatment of intrahepatic bile duct (IHBD) stones in patients after hepaticojejunostomy (HJ). Peroral direct cholangioscopy (PDCS) enables direct observation of the bile duct and is useful for detecting and removing residual stones; however, its effectiveness is not clearly established in this clinical context. Methods This single-center, single-arm, prospective study included 44 patients with IHBD who underwent bowel reconstruction with HJ during the study period. Stone removal was performed by short-type double-balloon enteroscopy (DBE). Following balloon-occluded cholangiography, the DBE was exchanged for an ultraslim endoscope through the balloon overtube for PDCS. The primary endpoint was the rate of residual stones detected by PDCS. Secondary endpoints were success rate of PDCS, residual stone removal with PDCS, procedure time for PDCS, procedure-related adverse events, and stone recurrence rate. Results PDCS was successful in 39/44 patients (89%), among whom residual stones were detected in 16 (41%) (95% CI: 28%–54%). Twelve patients (75%) had residual stones <5 mm. Stone removal was successful in 15 (94%) patients and median procedure time for PDCS was 16 (IQR: 10–26) min. The rate of procedure-related adverse events was 7% (3/44), all of which improved with conservative treatment. During median follow-up of 2.1 years (IQR: 1.4–3.3), the overall probability of recurrence-free status at 1, 2, and 3 years was 100%, 92%, and 86%, respectively. Conclusions PDCS is a safe and effective procedure for complete stone removal in patients with IHBD stones after HJ.
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