阿霉素
癌症研究
乳腺癌
癌症
医学
化疗
内科学
作者
Zhen Zhu,Hongyu Shen,Jialin Xu,Fang Zheng,Guanqun Wo,Ying Ma,Kai Yang,Yalin Wang,Qiang Yu,Jinhai Tang
标识
DOI:10.1016/j.drup.2023.100974
摘要
GATA3 promotes doxorubicin resistance by inhibiting CYB5R2-mediated iron metabolism and ferroptosis. Therefore, patients with breast cancer who display high GATA3 expression do not benefit from doxorubicin-based NAC regimens.
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