Formation of 2,3-Dihydrofurans via Bifunctional Biphenyl-2-ylphosphine Ligand Enables Gold-Catalyzed Cyclo-Isomerization of But-2-yn-1-ols or α-Allenols

In this work, we report a gold-catalyzed intramolecular cyclo-isomerization of but-2-yn-1-ols for the construction of 2,3-dihydrofurans under mild reaction conditions. The gold catalysis is enabled by a bifunctional phosphine ligand, and the reaction tolerates a range of substituents and exhibits good efficiencies.