免疫疗法
光热治疗
癌症免疫疗法
癌症
模式
声动力疗法
纳米载体
纳米医学
医学
癌症治疗
免疫系统
材料科学
纳米技术
癌症研究
免疫学
纳米颗粒
内科学
病理
社会科学
替代医学
社会学
标识
DOI:10.1002/adma.202308924
摘要
Abstract Cancer immunotherapy has become a promising method for cancer treatment, bringing hope to advanced cancer patients. However, immune‐related adverse events caused by immunotherapy also bring heavy burden to patients. Semiconducting polymer nanoparticles (SPNs) as an emerging nanomaterial with high biocompatibility, can eliminate tumors and induce tumor immunogenic cell death through different therapeutic modalities, including photothermal therapy, photodynamic therapy, and sonodynamic therapy. In addition, SPNs can work as a functional nanocarrier to synergize with a variety of immunomodulators to amplify anti‐tumor immune responses. In this review, SPNs‐based combination cancer immunotherapy is comprehensively summarized according to the SPNs’ therapeutic modalities and the type of loaded immunomodulators. The in‐depth understanding of existing SPNs‐based therapeutic modalities will hopefully inspire the design of more novel nanomaterials with potent anti‐tumor immune effects, and ultimately promote their clinical translation.
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