A comparative clinical study investigating the efficacy of a dentifrice containing 8% strontium acetate and 1040 ppm fluoride in a silica base and a control dentifrice containing 1450 ppm fluoride in a silica base to provide immediate relief of dentin hypersensitivity.

The 8% strontium acetate, 1040 ppm fluoride dentifrice provided significant within-treatment reductions in dentin hypersensitivity for all measures at both time points (immediate and three-day brushing). Compared to the control dentifrice, significant between-treatment reductions in sensitivity were observed after a single dab-on application for all measures, and following the additional twice-daily brushing for three days in favor of the 8% strontium acetate, 1040 ppm fluoride dentifrice.