Electrochemiluminescence Assay Based on Bipolar Electrode for Bioanalysis

Bipolar electrodes(BPEs) are electronic conductors which are usually embedded into microchannels. The potential difference at the BPE/solution interface is obtained by applying a voltage at the two ends of the microchannel. When it reaches a critical value, the redox reaction takes place at both poles of the BPE simultaneously. Compared with other detection methods, the electrochemiluminescence(ECL) platform based on BPE possesses the advantages of concentration enrichment, high sensitivity,low cost, portable sensor system, no need for a light source, which is quite suitable for bioanalysis. This paper reviews the ECL-BPE strategy for bioanalysis and proposes the future research trends.