表观基因组
表观遗传学
生物
丹麦语
疾病
后代
胚胎干细胞
生物信息学
遗传学
医学
怀孕
DNA甲基化
基因
基因表达
内科学
哲学
语言学
作者
Ida Donkin,Romain Barrès,Anja Pinborg
出处
期刊:PubMed
日期:2016-09-12
卷期号:178 (37)
被引量:1
摘要
The epigenome is sensitive to environmental changes and can sustainably alter gene expression, notably during embryonic development. New research indicates that epigenetic factors are heritable, which is why paternal lifestyle may affect fetal development and risk of disease. Children conceived by assisted reproduction technology (ART) have an increased risk of peri- and postnatal complications, and as specific ART protocols associate with specific risk profiles, the procedures themselves may cause epigenetic changes contributing to the altered outcomes of the 5,000 Danish children annually conceived by ART.
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