Nickel-Catalyzed Three-Component Carboamination of Internal Alkynes toward Tetrasubstituted Enamines and α,β-Unsaturated Imines

A nickel-catalyzed three-component carboamination strategy has been developed for the regio- and stereoselective synthesis of tetrasubstituted enamines from internal alkynes, organoboronic acids, and anthranils. This system also enables chemodivergent access to α,β-unsaturated imines by employing propargyl alcohols as versatile substrates.