Thermodilution-derived Recirculation and Cardiac Output Measurement during Veno-venous Extracorporeal Membrane Oxygenation: Do We Need More Bells and Whistles?

Editorial| May 2024 Thermodilution-derived Recirculation and Cardiac Output Measurement during Veno-venous Extracorporeal Membrane Oxygenation: Do We Need More Bells and Whistles? Michael Mazzeffi, M.D., M.P.H., M.Sc., F.A.S.A.; Michael Mazzeffi, M.D., M.P.H., M.Sc., F.A.S.A. 1University of Virginia School of Medicine, Department of Anesthesiology, Charlottesville, Virginia. Search for other works by this author on: This Site PubMed Google Scholar Jacob Gutsche, M.D. Jacob Gutsche, M.D. 2Penn Perelman School of Medicine, Department of Anesthesiology and Critical Care, Philadelphia, Pennsylvania. Search for other works by this author on: This Site PubMed Google Scholar Author and Article Information This editorial accompanies the article on p. 1002. Accepted for publication January 29, 2024. Address correspondence to Dr. Mazzeffi: Anesthesiology May 2024, Vol. 140, 887–889. https://doi.org/10.1097/ALN.0000000000004930 Connected Content Article: Modified Thermodilution for Simultaneous Cardiac Output and Recirculation Assessment in Veno-venous Extracorporeal Membrane Oxygenation: A Prospective Diagnostic Accuracy Study Views Icon Views Article contents Figures & tables Video Audio Supplementary Data Peer Review Share Icon Share Facebook Twitter LinkedIn Email Cite Icon Cite Get Permissions Search Site Citation Michael Mazzeffi, Jacob Gutsche; Thermodilution-derived Recirculation and Cardiac Output Measurement during Veno-venous Extracorporeal Membrane Oxygenation: Do We Need More Bells and Whistles?. Anesthesiology 2024; 140:887–889 doi: https://doi.org/10.1097/ALN.0000000000004930 Download citation file: Ris (Zotero) Reference Manager EasyBib Bookends Mendeley Papers EndNote RefWorks BibTex toolbar search Search Dropdown Menu toolbar search search input Search input auto suggest filter your search All ContentAll PublicationsAnesthesiology Search Advanced Search Topics: cardiac output, thermodilution, venovenous extracorporeal membrane oxygenation, extracorporeal membrane oxygenation Veno-venous extracorporeal membrane oxygenation (ECMO) has become a widely accepted therapy for adults with severe acute respiratory failure. According to the extracorporeal life support organization registry,1 veno-venous ECMO has been used to treat greater than 51,000 patients worldwide since 1990, and nearly 17,000 patients were treated worldwide during the COVID-19 pandemic. Although veno-venous ECMO allows for adequate arterial oxygenation to be achieved in most patients, in some cases, hypoxemia persists despite institution of ECMO. The effectiveness of veno-venous ECMO for improving blood oxygenation is contingent upon several factors including the relative matching of ECMO circuit blood flow with the patient's cardiac output. The amount of recirculation within the ECMO circuit also affects blood oxygenation. In a study by Schmidt et al.,2 10 adults with acute respiratory distress syndrome and constant mechanical ventilation settings had cardiac output serially measured using echocardiography during veno-venous ECMO. ECMO circuit blood flow... You do not currently have access to this content.