In order to solve the problem that the construction quality, efficiency, and seismic performance of assembled concrete frame structures are difficult to achieve, a new assembled monolithic frame structure system with "prefabricated nodes, prefabricated beams and columns, and post-cast Ultra-high Performance Concrete (UHPC) connections" is proposed. In order to study the seismic performance of the newnewly assembled frame, a 1:2 scaled-down static test was conducted on a cast-in-place frame and a prefabricated frame. The test results showed that the damage mechanisms of the cast-in-place frame and the precast frame were mixed damage mechanism and beam hinge mechanism, respectively, and the connection between each member by UHPC could improve the load-bearing capacity and pre-lateral stiffness of the precast assembled frame so that it has similar displacement deformation and energy dissipation capacity as the cast-in-place frame. Compared with the connection form of traditional precast frames, the mechanical properties of post-cast UHPC frames are improved and the avoidance of sleeve connection operation improves the construction efficiency, which can provide some reference for the design and engineering application of assembled concrete frame structures.