Treatments for Frontotemporal Dementia (FTD): A Network Meta-analysis

The term frontotemporal dementia (FTD) refers to a group of neurocognitive disorders that present with progressive decline in executive functioning, language, and behaviors. 1 Young JJ Lavakumar M Tampi D et al. Frontotemporal dementia: latest evidence and clinical implications. Ther Adv Psychopharmacol. 2018; 8: 33-48 Crossref PubMed Scopus (94) Google Scholar Overall, FTD is considered to be the 3rd most common etiology for dementia after Alzheimer's disease (AD) and dementia with Lewy bodies (DLB). However, among individuals <65 years of age, FTD is considered to be the second most common cause of dementia. Among individuals 45–65 years of age, the prevalence of FTD in the United States (US) is approximate, 15–22 per 100,000. Currently, in the United States, there are about 20,000–30,000 cases of FTD. The average age of onset is 45–65 years, with both men and women being affected equally. 2 Olney NT Spina S Miller BL Frontotemporal dementia. Neurol Clin. 2017; 35: 339-374 Abstract Full Text Full Text PDF PubMed Scopus (234) Google Scholar Approximately 25% of the cases of FTD occur among individuals >65 years of age. 1 Young JJ Lavakumar M Tampi D et al. Frontotemporal dementia: latest evidence and clinical implications. Ther Adv Psychopharmacol. 2018; 8: 33-48 Crossref PubMed Scopus (94) Google Scholar