Silver‐Catalyzed Decarboxylative Radical Cyclizations: Developments and Insights

Transition‐metal‐catalyzed decarboxylative cross‐coupling reaction provides a powerful method for the construction C‐C, C‐N, C‐O bonds, which have great impact on synthetic chemistry. The use of silver salts as catalyst in decarboxylative reaction gradually increases because of their easy availability, low toxicity, biocompatibility and adequate stability. In fact, various radical cyclization reactions have been accomplished by exploiting single electron transfer (SET) ability of silver salts. The present review highlights recent advances (2015‐mid 2023) in the silver‐catalyzed decarboxylative radical cyclizations for the construction of cyclic molecular scaffolds. The content of the review is organized on the basis of decarboxylative reagents, such as, α‐keto acids, aliphatic/aromatic carboxylic acids, α,α‐difluoroacetic acids, amino acids, alkynyl carboxylic acids, oxamic acids and miscellaneous acids. Additionally, mechanistic insights of most of the reactions are highlighted for well understanding of the reaction mode.