神经递质
脊髓损伤
脊髓
神经科学
神经干细胞
神经递质药
纳米载体
医学
中枢神经系统
药理学
化学
细胞生物学
干细胞
生物
药品
出处
期刊:Matter
[Elsevier]
日期:2023-10-01
卷期号:6 (10): 3129-3131
标识
DOI:10.1016/j.matt.2023.09.005
摘要
Treating spinal cord injury usually involves promoting axonal regeneration, but glial scars and other factors are insurmountable gaps. Activation of dormant relay pathways in the injected spinal cord is a new perspective on treatment. Although encouraging, due to the complexity of cell types in the remaining spinal cord, most drug carriers are only effective for a few spinal cord injuries. The nanocarrier disguised as a neurotransmitter has the effect of microenvironment ROS initiating targeted inhibition of a specific type of neuron, considering the binding of its neurotransmitter with neural inhibitors and encapsulating boron-based compounds. Treating spinal cord injury usually involves promoting axonal regeneration, but glial scars and other factors are insurmountable gaps. Activation of dormant relay pathways in the injected spinal cord is a new perspective on treatment. Although encouraging, due to the complexity of cell types in the remaining spinal cord, most drug carriers are only effective for a few spinal cord injuries. The nanocarrier disguised as a neurotransmitter has the effect of microenvironment ROS initiating targeted inhibition of a specific type of neuron, considering the binding of its neurotransmitter with neural inhibitors and encapsulating boron-based compounds.
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