耳毒性
二甲双胍
顺铂
医学
糖尿病
内科学
药理学
内分泌学
化疗
作者
Marc‐Elie Nader,Jonathan S. Choi,Mike Hernández,Katherine A. Hutcheson,Taylor Myers,Shirin Jivani,Rajarshi Pratihar,Katharine Fernandez,Jack Phan,Cindy You,Paul W. Gidley
摘要
Ototoxicity is an important side effect of cisplatin. Recent animal and in vitro studies suggest metformin may protect hearing, though human studies are lacking. We report the first retrospective clinical study exploring the effects of metformin on cisplatin-induced ototoxicity.
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