Trachelectomy and fertility-sparing procedures for early-stage cervical cancer: A state of the science review

Cervical cancer is the most common gynecologic malignancy worldwide. An estimated 604,127 women were diagnosed with cervical cancer in 2020, and 341,831 women died from the disease [1]. Cervical cancer is more frequently diagnosed at a younger age (30–40 years) compared to other gynecologic malignancies. Over 60% of patients are diagnosed with localized disease, for which surgery can be curative [2]. Surgery traditionally includes radical hysterectomy with nodal assessment, although data from the SHAPE and ConCerv trials suggest simple hysterectomy or conization may be safe for select patients with stage IA2-IB1 disease and tumors ≤2 cm [3,4].