羧甲基纤维素
阿维菌素
化学
控制释放
纳米颗粒
化学工程
药物输送
纤维素
肺表面活性物质
傅里叶变换红外光谱
材料科学
Zeta电位
生物化学
纳米技术
有机化学
生物
解剖
钠
工程类
作者
Huaxin Zhu,Yue Shen,Jianxia Cui,Anqi Wang,Ningjun Li,Chong Wang,Bo Cui,Changjiao Sun,Xiang Zhao,Fei Gao,Shenshan Zhan,Liang Guo,Lei Zhang,Zhanghua Zeng,Yan Wang,Haixin Cui
标识
DOI:10.1016/j.indcrop.2020.112497
摘要
Abstract Polyethylene glycol (PEG) was introduced into carboxymethyl cellulose (CMC) to form hydrophilic chain of PEG-CMC. Avermectin (Avm) was grafted on the long chain of PEG-CMC by use of N, N-dicyclohexylcarbodiimide (DCC) as the dehydrant and 4-dimethylaminopyridine (DMAP) as the catalyst to form the amphiphilic molecule. Then the avermectin nanoparticles was prepared with esterase-responsive sustained release successfully through self-assembly. The size of nanoparticles was less than 400 nm. Avermectin loading was 8% and the degradation rate was less than 50 % under the xenon arc lamp for 72 h. Compared with avermectin technical, it showed an obvious anti-photodegradation advantage. Compared with commercially available water-dispersible granules (WDG), the avermectin nanoparticles had a smaller contact angle on the cucumber leaf surface and there was a significant difference. The toxicity test showed that the nanoparticles have a certain insecticidal effect on the larva of Hyphantria cunea and the sensitivity increased gradually over time.
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