医学
四分位间距
心肌病
优势比
置信区间
内科学
诊断代码
回顾性队列研究
儿科
心脏病学
心力衰竭
人口
环境卫生
作者
Prithvi Sendi,Paul Martinez,Madhuradhar Chegondi,Balagangadhar R. Totapally
出处
期刊:Cardiology in The Young
[Cambridge University Press]
日期:2020-08-26
卷期号:30 (11): 1711-1715
被引量:6
标识
DOI:10.1017/s1047951120002632
摘要
Abstract Objective: To explore the epidemiology and outcomes of takotsubo cardiomyopathy in children. Methods: A retrospective analysis of the Healthcare Cost and Utilization 2012 and 2016 Kids’ Inpatient Database was performed. Patients admitted with the diagnosis of takotsubo cardiomyopathy in the age group of 1 month–20 years were identified using International Classification of Diseases (ICD)-9 code 429.83 and ICD-10 code I51.81. Results: Among a total of 4,860,859 discharges, there were 153 with the diagnosis of takotsubo cardiomyopathy (3.1 per 100,000 discharges). Among patients with takotsubo cardiomyopathy, 55.0% were male, 62.4% were white, and 16.7% were black. Eighty-nine percent of patients were between 12 and 20 years. Psychiatric diagnosis was documented in 46% and substance use disorder in 36.2%. Sepsis was documented in 22.8% of patients. The median length of stay was 5 days (interquartile range: 2.7–15), and median total charges were $75,080 (interquartile range: 32,176–198,336). The overall mortality for takotsubo cardiomyopathy was 7%. On multivariable regression analysis, mortality was higher in the presence of anoxic injury (odds ratio = 34.42, 95% confidence interval: 4.85–320.11, p = 0.00). Conclusions: Takotsubo cardiomyopathy is uncommon in children and carries a mortality rate of 7%. Most children with takotsubo cardiomyopathy are adolescent males, many of whom have psychiatric disorder or substance use disorder or both. Takotsubo cardiomyopathy should be considered in the differential diagnosis for patients who present with cardiac dysfunction and have underlying psychiatric disorders or drug abuse.
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