Research progress in decellularized matrix material for tissue engineering

Extracellular matrix(ECM)plays an important role in regulation of stem cell differentiation and in induction of reconstruction of new tissue and organ.To obtain the acellular matrix materials from different sources by different decellularized methods in vitro and study the application of them in tissue engineering are significant to the theoretical research and clinical application.This study summarized the methods of decellularized matrix material from different sources.Its role in the induction of stem cell differentiation and tissue repair process was also analyzed.Finally,the current problems and challenges in the acellular of matrix material were discussed.