IMMUNOADSORPTION THERAPY IN MYASTHENIA GRAVIS

Objective To investigate the therapeutic effect and safety of immunoadsorption therapy in patients with myasthenia gravis.Methods 40 patients with myasthenia gravis were randomly divided into two groups: control group (n=20) received conventional treatment, and Immunoadsorption therapy group (n=20) received Immunoadsorption therapy base on the treatment of control group.Two group were compared with Serum AchR-Ab,IgG、IgA、IgM, MG-MMT, clinical efficacy and safety.Results Compared with the control group, Immunoadsorption therapy group Serum AchR-Ab,IgG、IgA、IgM Significantly reduced (p0.05), MG-MMT scores were significantly lower(P0.05), and better clinical efficacy (p0.05); two groups of patients had no serious adverse reactions.Conclusion Patients with myasthenia gravis received treatment of immunoadsorption have better clinical effective, It is worthy of promotion.